The aim of this study is to analyze the factors affecting the acceptance of electronic health on the basis of the theory of planned behavior. E-health is a growing field of health communication that entails using medical informatics, public health, and trades. As a result, E-health facilitates the provision of health information and services through the internet and related technologies. In this regard, this study aims to explain the acceptance of e-health by its beneficiaries such as physicians, patients, and healthcare managers. The results have shown that the most important factors affecting the acceptance of e-health are: 1. Organizational related factors of e-health services; 2. Human-related factors of acceptors; 3. Environment-related factors; 4. Factors associated with financial sources and expenditures; 5. Technical and infrastructural factors. Taking advantage of interpretive structural modeling, we demonstrated these factors and determined the level of their reciprocal relations.
